This marks the second week in a row that the ABC News program prevailed over the Nos. 1- and 2-ranked late-night shows, which have been in reruns since the beginning of the writers' strike.
The last time Nightline prevailed over its sketch-comedy competition for two weeks in a row was in May 1995.
Nightline pulled in 3.91 million viewers (1.97 of them in the demo) compared with Leno's 3.41 million and Letterman's 3.1 million, according to Nielsen Media Research.
For full coverage of the strike, click here.