The series’ Katherine Heigl (Izzie Stevens) was named favorite female star, while Patrick Dempsey (Derek "McDreamy" Shepherd) was the favorite male star. Chandra Wilson (Miranda Bailey) won favorite scene stealer for her role as mother hen/taskmaster of the Grey's bunch.
Best TV drama went to Fox's House, which combines scalpels with the razor-sharp cynical edge of its main character.
Moving out of the operating room (sorry, Scrubs), CBS' Two and a Half Men was named favorite sitcom, while ABC's Dancing with the Stars was named favorite reality show. NBC's Deal or No Deal got the nod for game show, while Sci Fi Channel’s Stargate Atlantis was the favorite science-fiction series.
Fox's The Simpsons won in the animated-series category, and Ellen DeGeneres was named favorite talk-show host.
With TV writers on strike, the People's Choice organizers changed the format, taping the show and sending camera crews to nominees to tape their acceptance speeches so that none would have to worry about crossing potential picket lines to participate in the broadcast.